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A Crispr Conundrum: How Cells Fend Off Gene Editing

Carl Zimmer New York Times
Crispr has stirred strong feelings ever since it came to light as a gene-editing technology five years ago. Already, it’s a mainstay in the scientific tool kit. But recent studies remind everyone that genome editing isn’t magic.

Obesity Breakthrough: Genetic Alchemy Can Turn Bad Fat Cells to Good

Massachusetts Institute of Technology
Obesity is one of the biggest public health challenges of the 21st century, affecting more than 500 million people worldwide and costing at least $200 billion each year in the United States alone. It contributes to cardiovascular disease, type 2 diabetes, and cancer. Scientists have now uncovered a genetic circuit that controls whether our bodies burn or store fat. Manipulating that genetic circuit may offer a new approach for obesity treatments.

Viking Women Travelled Too, Genetic Study Reveals

Daniel Zadik The Conversation
Until recently, [some] specimens have been un-sequenceable due to DNA contamination from the modern people who have handled them. Today’s techniques make it possible to differentiate modern from ancient DNA sequences, which opens up the prospect of returning to the many museum specimens in collections worldwide to see what further answers they might hold.

How Exercise Changes Our DNA

Gretchen Reynolds The New York Times
Exercise, a new study finds, changes the shape and functioning of our genes, an important stop on the way to improved health and fitness. More than 5,000 sites on the genome of muscle cells are altered by exercise.
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